Offers assured sterilization with internal multi-variable indicator and an external process indicator for steam sterilization. Meets CDC guidelines for effective sterilization and responds to all variables: Time, Temperature and Saturated Steam. Secure seal with extra-wide chevron seal protects against instrument breaching while high quality porous medical-grade paper meets medical standard. Perforated fold facilitates easy and accurate folding of adhesive strip to form airtight seal. Thumb notch enables easy opening of the pouch.